[3] They established the first Community Oriented Primary Care (COPC) program and health centre in South Africa[4][5][6][7][8] in a Zululand rural area, where Kark grew up until 1946.

[3] Kark attended Westville Boys' High School in Durban, and moved with his family to Chapel Hill, North Carolina, USA in 1957.

In 1959, Kark's parents immigrated to Jerusalem, where they worked to establish the Department of Social Medicine of the Hebrew University and Hadassah Medical Organization.

[17] He also served as the Director of the Legacy-Heritage International MPH Program, Hebrew University-Hadassah School of Public Health and Community Medicine in 2006 –2007.

[23][24][25] As a high school and university student, Kark actively competed in various branches of sports, including cricket, rugby and swimming.

[29] In 2018, following Kark's death, his wife established “The Jeremy D. Kark Legacy Prize for Academic Excellence”, awarded annually to an International Master of Public Health (IMPH) student at the Hebrew University – Hadassah School of Public Health and Community Medicine in recognition of outstanding academic and research performance.