Jerome is an uninhabited community along the old Baltimore and Ohio Railroad main line in Morgan County in the U.S. state of West Virginia.

It is located entirely within the Chesapeake and Ohio Canal National Historical Park on the Potomac River.

When it was abandoned by the Chessie System in May 1975, the office was not torn down and is one of the few buildings that remain today in Jerome.

The community and its station on the railroad are rumored to have been named for Jérôme Bonaparte.

This article about a location in Morgan County, West Virginia is a stub.