In his senior season, Simpson won team MVP and set a championship record with 13 receptions for 133 yards and also added a 62-yard touchdown pass.

[citation needed] Jerome Simpson enrolled at Coastal Carolina University in 2004 and started all 11 games as a true freshman at receiver.

In the season opener against Morehead State, Simpson recorded four catches for 59 yards and two scores in his collegiate debut.

He finished the season with 26 catches for 419 yards and eight touchdowns and was honored as the Big South Conference Freshman of the Year.

In his best game of the season, a victory over James Madison, Simpson set a school record with 10 receptions for 162 yards and two touchdowns.

In the school's first ever Division I-AA NCAA Football Playoff appearance, Simpson recorded 132 yards and two touchdowns against No.

Due to injuries to Terrell Owens and Chad Ochocinco, Simpson made his second career start in Week 16 of the 2010 season and had a breakout performance, catching 6 passes for 124 yards and 2 touchdowns.

In Week 16 of the 2011 season, Simpson did a front-flip over Arizona Cardinals linebacker Daryl Washington to score a touchdown and landed on his feet.

[11] Simpson was suspended for six games due to violating the leagues substance abuse policy stemming back to a 2014 arrest.

[13] In September 2011, police searched Simpson's Crestview Hills, Kentucky townhome after intercepting a package to be delivered to his home containing 2.5 pounds of marijuana.

After the search warrant was issued, the police found 6 more pounds of marijuana, scales, and empty packages similar to the one they had intercepted.

[14] On January 19, 2012, Simpson was indicted in Covington, Kentucky for "Trafficking in more than eight ounces and less than five pounds of marijuana", a Class D felony, which carries a 1 to 5-year prison sentence if convicted.