Many of his siblings also became involved in music, most notably his brother, Walter, who played drums on some early recordings.

[1] McCain picked up the harmonica from itinerant musicians "Chick" and "Shorty" who played at the local bars (and street corners) when he was young.

During his time with Ichiban, McCain also released one record on the Jericho label, This Stuff Just Kills Me, which featured John Primer, Jimmie Vaughan, and Johnnie Johnson.

McCain's inclusion in the Blues Master series, was alongside Little Walter, Jimmy Reed, Junior Wells, Howlin' Wolf, Snooky Pryor, and George "Harmonica" Smith.

"Concerto for Blues Harmonica and Orchestra" was premiered in November 1996, on the EYO's Fall Formal Concert at Wallace Hall, on the campus of Gadsden State Community College.