In interwar Poland he joined the Stronnictwo Demokratyczne (Polish Democratic Party); he became known for his strong opposition to anti-semitic events.

At a meeting between Arciszewski and the Prime Minister of the United Kingdom, Winston Churchill, Lerski gave a detailed report on the plight of the Jews in Poland.

After 8 May 1945, when World War II ended in Europe, Lerski decided to remain in London instead of returning to Soviet-dominated communist Poland.

The State of Israel recognized him as a Righteous Among the Nations, an honor given to non-Jews who risked their lives during the Holocaust to save Jews from extermination by the Nazis.

The citation read, "Jerzy Jan Lerski ... informed political circles abroad about the extermination and persecution of Jews.

"[2] George Lerski died following coronary bypass surgery on 16 September 1992 at the Veterans Hospital in San Francisco, California.