Jesse is an American sitcom television series created by Ira Ungerleider and starring Christina Applegate, that ran on NBC from September 24, 1998, to May 25, 2000, for two seasons of a total 42 episodes.

The show stars Christina Applegate as single mother Jesse Warner, raising her twelve-year-old son, Little John, in Buffalo, New York.

She works for her overbearing father in a German-themed bar, serving beer while wearing a dirndl.

Jesse's love interest, a Chilean named Diego (Bruno Campos), gains a rival when her ex-husband comes to town, intent on winning her back.

While Jesse was in the top 20 in the Nielsen ratings regularly, the show lost much of the audience from Friends, its powerful lead-in.