Jesse Leonard Steinfeld (January 6, 1927 – August 5, 2014) was an American physician and public health official.

Steinfeld then completed an internship at Cedars of Lebanon Hospital in Los Angeles and residencies at the Veterans Administration Hospital in Long Beach, California, and at the University of California, San Francisco in the Laboratory of Experimental Oncology.

From 1954 to 1958, he served as director of the radioisotope laboratory of the National Cancer Institute, National Institutes of Health, and simultaneously held an appointment as instructor in medicine at the George Washington University School of Medicine.

He was appointed deputy assistant secretary for health and scientific affairs, and surgeon general beginning December 18, 1969.

During his tenure, there was an effort to do away with the Public Health Service Commissioned Corps, and a 1971 report made such a recommendation.

At the beginning of the second Richard Nixon administration, Steinfeld resigned as surgeon general effective 30 January 1973.