She began her acting career at the age of 7, being cast as Pam Ferris's daughter, Lucy Snow, in the popular ITV series Where The Heart Is.
Further parts in New Street Law and a semi regular role in TV soap Emmerdale followed in 2007, before at the age of 18 Baglow was cast as Karla Bentham in Waterloo Road.
Her portrayal of a student with Asperger syndrome won acclaim and gained her considerable notice during her three years on the show, as she began to progress from child roles to more adult subjects.
[5][6] Dominic Cavendish of The Daily Telegraph wrote: "Jessica Baglow is a big find as Pericles's daughter Marina – calmness and dignity personified in her perturbing scenes of abduction and sexual exploitation.
"[7][8] In 2019, she appeared in the acclaimed BBC series Gentleman Jack, about the lesbian diarist and noblewoman Anne Lister, playing her ladies maid Hemingway.