She rose to fame in Australia playing roles in the Seven Network television programs Home and Away and Packed to the Rafters.

Her film roles include The Vow (2012), Chips (2017), Battle of the Sexes (2017), The Meg (2018) and Mortal Kombat (2021).

She played the role of Theresa Kelly, a Chicago police officer, and was a main character in the show.

[8] In 2018, McNamee played the lead role of Jenna alongside William Fichtner in the drama film The Neighbor.

[9] She played Lori, the ex-wife of megalodon hunter Jonas Taylor (Jason Statham), in the blockbuster The Meg.

[10] In August 2019, McNamee was cast in Mortal Kombat as Sonya Blade and it was released in April 2021.

[13] She also provided voice work in Rhys Wakefield's drama podcast series titled From Now.