She played professionally in National Pro Fastpitch and was named 2011 Player of the Year and currently ranks in the top 10 for career batting average and slugging percentage.

Mendoza was named by fans and experts to the Greatest College Softball Team as an outfielder, one of only three to achieve the honor.

[3] Mendoza, a graduate of Adolfo Camarillo High School, was named the Los Angeles Times Player of the Year in 1998.

[4] On March 6, 1999, in defeating Illinois State, Mendoza had a single-game career high four hits off pitchers Corey Harris, Tammy Millian and Jamie Bagnall.

[8] She added conference Player of the Year to her collection and broke her own record for batting average with a then-school and career-best .474, which also led the NCAA.

[9] She also claimed new records for hits, home runs, doubles, slugging, and stolen bases, which still rank top 10 for a season at Stanford.

[11] She posted top-10 season records in virtually every category, still currently ranking second in single-season home runs and stolen bases.

[13] With her fourth straight honor from the NCAA, Mendoza joined elite company as only the fifth player to accomplish the feat then.

Mendoza was shut out against the Chicago Bandits' trio of Kristina Thorson, Nikki Nemitz, and Jessica Sallinger.

[33] On June 16, 2015, Mendoza became the first female broadcaster in the booth for ESPN's College World Series coverage with Karl Ravech and Kyle Peterson.

[35] Six days later, Mendoza filled in for suspended color commentator Curt Schilling for the Cubs–Dodgers game on Sunday Night Baseball.

[36][37] On January 13, 2016, ESPN announced that Mendoza would join the Sunday Night Baseball broadcast team full-time, with Shulman and Aaron Boone.

[2] On October 6, 2017, Mendoza commentated for the 2017 NLDS, her first MLB post-season series, on ESPN Radio with broadcast partner Dave Flemming.

[citation needed] On March 5, 2019, the New York Mets announced that Mendoza joined the club as a senior advisor to general manager Brodie Van Wagenen.

[39] On January 16, 2020, she created controversy when she criticized former Houston Astros pitcher Mike Fiers for admitting to stealing signs during the team's World Series title run in 2017.

[43] Amid concerns about a potential conflict of interest over her Mets role and the controversy of the Fiers comments, she later resigned from her role as Mets advisor and was dropped from Sunday Night Baseball, but signed a contract extension with ESPN on February 7, 2020, to remain a baseball analyst with the network.

[48] In March 2022, it was announced that Mendoza would join the Spectrum SportsNet LA network to provide commentary for Los Angeles Dodgers games.

She was a part of a group of network additions that included Eric Karros, Adrián González, José Mota, and Dontrelle Willis.

[citation needed] She is a second-generation Mexican-American, as stated in an ESPN article by Aimee Crawford published on October 11, 2011.