[5] Lisa and Jessica impressed music executive Hayden Bell with their demo tracks, and were signed to Excalibur Productions Australia as songwriters in 2004.

[9] By the end of 2004 they travelled to America and signed with Sire Records, a subsidiary of Warner Music for a deal worth $2 million.

[13] The following year, they released their debut album The Secret Life of... (2005), which spawned their first major hit "4ever" peaking at number two on the ARIA Singles Chart and certified platinum, denoting 70,000 copies shipped in Australia.

[27] Months after this performance, in 2012, The Veronicas finally revealed that they would release a new song called "Lolita" for their new album, which was known as Life on Mars at the time.

[29][30] Life on Mars was to be released by the end of 2012, however, Warner Music pushed the date back to early 2013, and eventually the record was shelved altogether.

[31][32] Because of this, Lisa and Jessica hired a lawyer in a bid to get out of their contractual obligations with the label and were successful, so by 2013 The Veronicas became an independent act.

[47] They released Gothic Summer in 2024 [48] They also did a reality show for MTV in 2019, called: The Veronicas: Blood Is for Life[49] Origliasso was in a relationship with Ruby Rose in 2008.

[58] In 2006, Origliasso and her sister, Lisa, joined Steve Irwin's Wildlife Warriors Worldwide, as ambassadors for charity that promotes the protection of animals and their natural environments.

[59] In January 2009, Origliasso was asked to pose nude for PETA; this came after she was seen on the New York City Subway wearing a faux fur jacket with an anti-fur message on the back.

[65][66][67] Origliasso has raised extensive awareness for Sea Shepherd internationally, visiting their ships and performing at their funding events.