Vosk is best known for her performance as the lead role of Elphaba Thropp in Wicked, which she played on Broadway at the Gershwin Theatre from July 2018 to May 2019 (a period that included the show's 15th Anniversary).

[10] [11] From The Bridges of Madison County she went to Finding Neverland, in which she was in the original Broadway production playing the role of Miss Bassett and an understudy for Mrs. du Maurier.

[15] Vosk left Fiddler on The Roof in 2016 to join the cast of the Second National Tour of Wicked succeeding Emily Koch in the lead role of Elphaba Thropp.

[16][17] She made her debut in South Bend, Indiana on September 7, 2016, opposite Amanda Jane Cooper as Glinda Upland.

On June 18, 2018, it was announced that Vosk would reprise the role of Elphaba in the Broadway production of Wicked, succeeding Jackie Burns.

[22] On February 17, 2020, Vosk appeared as one of The Narrators in the 50th Anniversary concert of Joseph and the Amazing Technicolor Dreamcoat at Lincoln Center.

The album is a mix of musical theatre and pop and includes songs by Sara Bareilles, Jason Robert Brown, Prince, Sia, Pasek and Paul, and more.

It would feature Vosk performing her take on Holiday favorites along with special guests Neil Patrick Harris, David Foster, Ariana DeBose, and Scott Hoying.

Her sophomore cabaret act You Asked for It would debut in February 2016 at Joe's Pub featured Vosk performing a lot of diva-based anthems that inspired her wanting to become a gay icon.

On November 8, 2021 Vosk made her solo debut at Carnegie Hall with a program entitled My Golden Age playing to a sold-out audience.

Following the success of her solo debut there, Vosk would continue to develop a strong relationship with Carnegie Hall including a 2022 return performing a tribute concert to Judy Garland commemorating her 100th Birthday entitled Get Happy, a concert she previously also performed in San Francisco, CA with the San Francisco Symphony.

[38] Since the New York premiere, Vosk has continued to perform the concert doing multiple configurations with a small band or a symphony orchestra.