His film appearances include When the Game Stands Tall (2014), Teenage (2013), Independence Day: Resurgence (2016), Shaft (2019), and Smile (2022).

[3][4] Usher showed an interest in acting at the age of five after his sister Jesstia booked a TV commercial.

The film spawned a television series in which Usher would reprise his role as Lyle Hugginson which lasted two seasons.

In March 2014, Usher was cast as the lead in Survivor's Remorse, executive produced by NBA player LeBron James.

[13] In January 2018, it was announced that Usher has been cast as Reggie Franklin / A-Train in the Amazon Studios series The Boys, which is based on Garth Ennis and Darick Robertson comic book with the same name.