Durán signed with the Arizona Diamondbacks as an international free agent in December 2014.

He made his professional debut in 2015 with the Dominican Summer League Diamondbacks.

On July 27, 2018, the Diamondbacks traded Durán, Gabriel Maciel and Ernie De La Trinidad to the Minnesota Twins in exchange for Eduardo Escobar.

[4] Due to the COVID-19 pandemic, he did not participate in any minor league games in 2020, as the season was cancelled.

[5] On April 4, 2022, it was officially announced that Durán had secured a spot on the Twins’ Opening Day roster.