The park provides sanctuary for 37 known species of mammals including several endangered, threatened or vulnerable species, such as the Bhutan takin, snow leopard, clouded leopard, Bengal tiger, bharal or Himalayan blue sheep, black musk deer, Himalayan black bear, red panda, Ussuri dhole, and spotted linsang.

It is also the only park in Bhutan where the national animal (takin), flower (blue poppy), bird (raven) and tree (cypress) exist together.

[3][4] Jigme Dorji National Park covers most of northern Gasa District, including the bulk of Lunana and Laya Gewogs.

These glaciers have thawed significantly over the course of recorded history, causing lethal and destructive glacial lake outburst floods.

[8] As the seasons allow, temporary camps of laborers work within the park to reduce water levels to assuage the threat of flooding downstream.