Although leading the American Association in batting average, runs, hits and doubles in 1977 for the Wichita Aeros,[3] the Cubs' AAA affiliate, he was released on September 7, 1977 and signed a contract with the Cardinals a week later.

After two seasons with the Red Sox (1979–80), Dwyer signed a three-year free agent contract with the Baltimore Orioles.

[5] With Baltimore, Dwyer became one of Manager Earl Weaver's key platoon players, primarily used as a corner outfielder, designated hitter and pinch-hitter.

[6] In a 13–11 loss to the Texas Rangers at Memorial Stadium on August 6, 1986 which was the first-ever game in MLB history that featured three grand slams, Dwyer hit one in the fourth off Jeff Russell after Larry Sheets had done likewise off Bobby Witt earlier in the same inning.

Following his playing career, Dwyer coached (1991) the Triple A Portland Beavers and then managed theKenosha Twins (1992) and Fort Wayne Wizards (1993–94) .