DeGrasso played with Mama's Boys and Lita Ford before eventually working with Y&T and Megadeth and as a session and touring musician for Ozzy Osbourne (1986), White Lion (1991), Fiona (1992), Suicidal Tendencies (1992–1995), MD.45 (1996), and Alice Cooper (1995–1997).

[1] After Megadeth broke up around 2002, DeGrasso worked with Dave Ellefson's F5 (2007–2010) and toured with The David Lee Roth Band (2006), Ministry (2008), Alice Cooper (2008), Hail (2009), Dokken (2012), and Ratt (2014).

[citation needed] DeGrasso then joined the veteran metal band Y&T in 1986, replacing their original drummer Leonard Haze.

In 1998, Mustaine asked him to join Megadeth to replace Nick Menza as drummer and continue the band's Cryptic Writings tour.

[citation needed] In late 2008, DeGrasso came back to Alice Cooper's band to fill in for Eric Singer while Singer played a few KISS shows in the U.S. DeGrasso has also been the full-time drummer for heavy metal band F5 and Hail (along with ex-Megadeth bassist David Ellefson).