[7] In the late 1940s, Holton worked for two years in the Central Intelligence Group at the American Embassy in Brussels, Belgium.
[7] After returning from Belgium, she worked for two years at the Central Intelligence Agency in Washington, D.C., reporting to James Jesus Angleton.
Holton and her husband made national headlines when, after moving to the Virginia Executive Mansion, they enrolled their children in Richmond Public Schools, which had recently been integrated.
[4][10][2] As First Lady, Holton's primary causes included child nutrition and daycare programs, civil rights, and the integration of public schools.
[7] Holton moved with her family to northern Virginia in 1974, when her husband accepted a job as Richard Nixon's Assistant Secretary of State for Congressional Relations.