Jishou (Chinese: 吉首; pinyin: Jíshǒu; Tujia: Jiersouv) is a county-level city and the seat of Xiangxi Tujia and Miao Autonomous Prefecture, Hunan province, China.

In 1982 Jishou city became the capital of Xiangxi Tujia and Miao Autonomous Prefecture.

The highest elevation is 964.5 meters, at Liantaifeng (莲台峰; 蓮台峰, near the town of Aizhai (矮寨) and the lowest point is 142 meters, near the town of Hexi (simplified Chinese: 河溪镇; traditional Chinese: 河溪鎮).

Members of China's predominant Han ethnic group comprise the rest of the population.

Jishou produces fruits, especially kiwis and oranges, vegetables, livestock and poultry, and tobacco.