His godfather, Dom Diogo de Noronha, 3rd Marquess of Marialva and 5th Count of Cantanhede by marriage, was represented at the ceremony by his son Dom Rodrigo António de Noronha e Meneses.
Chief of Lineage, he graduated in Law and became a Fidalgo-Knight of the Royal Household by letters patent (Alvará) of March 2, 1737, becoming a Knight of the Order of Christ on April 26, 1769.
His legal roles included being a Corregedor of the Crime of the Court and House of the Supplication, Desembargador of the House of the Supplication of the Palace and of the King, and he was also Commander da Lezíria do Corvilho in the Order of Christ, Member of the Royal Brotherhood of Santa Cruz and Passos da Graça.
He was the last possessor of the old Mouzinho house and farm in Chelas, Lisbon, which he appears to have sold in the middle or end of 1788 to Manuel Joaquim de Freitas, who is thought to be an ancestor of the 1st Viscount of Vila Gião.
Mouzinho de Albuquerque died in 1802 and was buried at the Church of São Francisco of Leiria.