[6] She stayed in the Portland, Oregon area[7] for several years, where she worked as a freelance artist for Dark Horse Comics and Oni Press.

[11] In 2008, Minx (a short-lived DC Comics imprint) published the graphic novel Token, which was written by Alisa Kwitney and illustrated by Jones.

[12][13][14] In 2010, Dark Horse published Troublemaker, a graphic novel continuation of Janet Evanovich's Barnaby series; Jones created the artwork.

In 2015 Dark Horse Comics published Lady Killer, a miniseries Jones illustrated and co-wrote with Rich about a 1960s housewife who moonlights as an assassin, later collected in trade paperback form.

In 2016, Jones received three Eisner Awards nominations for her work on Lady Killer and on Brides of Helheim: Best Limited Series, Best Penciller/Inker, and Best Cover Artist.

[23] In September 2017, artwork inspired by Jones's style was used as part of the runway backdrop at Prada's spring 2018 exhibition in Milan.

[33] In July 2017, DC announced that Jones would draw both the covers and interior art for the DC Rebirth version of Batman, starting with issue #33,[34] making her the first female artist to draw covers and interior pages on more than two consecutive Batman-centric issues in the character's history.

[43] In January 2024, it was announced that Jones would serve as one of the artist for the 2024 relaunch of the IDW Teenage Mutant Ninja Turtles series written by Jason Aaron.