JoAnn Elisabeth Manson (born 1953) is an American physician and professor known for her pioneering research, public leadership, and advocacy in the fields of epidemiology and women's health.

[1] She is the Michael and Lee Bell Professor of Women's Health at Harvard Medical School, a professor of epidemiology in the Harvard School of Public Health, and chief of the Division of Preventive Medicine at Brigham and Women's Hospital.

In high school she showed interest in chemistry, as well as in artistic pursuits including painting, sculpture, and the harp.

Manson is also the principal investigator of the multi center COSMOS trial to study the effects of cocoa and multivitamin supplementation on cardiovascular disease and cancer.

In several large scale prospective cohort studies and randomized clinical trials, Manson has assessed the role of lifestyle factors and therapeutic interventions in the prevention of chronic disease in women.