[5] In 2006 she wrote and starred in her own comedy sketch show called Little Miss Jocelyn, a second series of which aired in January 2008.
[5] In 2007, Esien featured in Girls Aloud and Sugababes' Comic Relief video for "Walk This Way",[8] where she puts a parking ticket on Ewen Macintosh, a reference to the character Jiffy from the show Little Miss Jocelyn.
Esien's other TV appearances include Autumn Leaves, a BBC comedy-drama; Some Girls, Uncle Max, After You've Gone, Holby City, The Lenny Henry Show, Ed Stone Is Dead, Comedy Nation, The Fast Show, Douglas, The Bill and In The Name of Love (TV movie).
[16] She appeared in the 2010 film StreetDance 3D and wrote an episode of the American reality TV show Jon & Kate Plus 8.
[17] She also appeared in the BBC comedy Big School as Headmistress Ms Baron's (Frances de la Tour) personal assistant and secretary named Daphne, from 2013 to 2014.