He played in Major League Baseball as a pitcher for the Chicago White Sox and Cincinnati Reds during the mid-1970s.

[3] Early in his professional career, he converted to pitching, posting a 17–8 win–loss record at the Class A level in 1968,[3] but he missed most of the 1969 season due to injury.

[6][7] Henderson played parts of three seasons in the major leagues, in 1974 with the Chicago White Sox and in 1976 and 1977 with the Cincinnati Reds, exclusively as a pitcher.

[3] Overall, in 16 major-league games (three starts), Henderson compiled a 3–2 record with a 6.69 earned run average (ERA) while striking out 27 batters in 35 innings.

[1] During his minor-league career, Henderson compiled an 80–49 record in 276 games pitched (111 starts), posting a 3.24 ERA while striking out 831 batters in 1085 innings.