At the age of twenty he went to Berlin, where he received instruction from Isaac Satanow, who was a follower of Moses Mendelssohn.
Mendelssohn's influence was doubtless instrumental in securing for Löwe the position of tutor in the house of the influential David Friedländer.
Jointly with Aaron Wolfsohn he edited Ha-Meassef, in which periodical he published a large number of poems and essays.
In company with Aaron Wolfsohn, Löwe published Mendelssohn's German translation of the Song of Solomon with a Hebrew commentary.
He wrote also on chronology, and was a contributor to Johann Gottfried Eichhorn's Allgemeine Bibliothek der Biblischen Literatur.