[3] With a fallen ranking of 55th by the NHL's Central Scouting Final grades, Hishon was surprisingly taken in the first round, 17th overall, by the Colorado Avalanche.

[9] Hishon's recovery extended into the following 2012–13 season, before he was belatedly cleared for non-contact practice with the Avalanche's AHL affiliate, the Lake Erie Monsters, to begin the new year.

[12] However, on April 12, in his ninth game and on his first shift against the Hamilton Bulldogs, Hishon's season was ended after he suffered a second concussion received in a hit from behind by Joey Tenute.

With an early prognosis of a less severe concussion than previously endured, it was anticipated Hishon would recover in time to prepare for the following season.

[15] At the end of the season, the Avalanche gave him a qualifying offer of $900,000,[16] and he was reportedly signed to a one-year two-way contract paying $850,000 in the NHL.

[20] In the 2015–16 campaign, he made 62 appearances for Colorado's AHL affiliate, the San Antonio Rampage, unable to earn a recall to the NHL for the duration of the season.

On May 2, 2016, as an impending restricted free agent with the Avalanche, Hishon opted to embark on a European career, signing two-year deal with Finnish club, Jokerit, who compete in the Kontinental Hockey League.