He played college football at Houston, and was signed by the Falcons as an undrafted free agent in 2015.

He recorded 67 tackles, two sacks and two blocked field goals his senior year.

Mbu also participated in discus and shot put on the school's track team.

He played in twelve games, recording four total tackles, his freshman season in 2011.

[1][3] Mbu played in 50 games, starting 38, during his college career and recorded 92 tackles, four sacks, eight pass breakups, and two interceptions.

[5] Lance Zierlein of NFL.com predicted that he would be selected in the seventh round or be a priority free agent.

Zierlein also stated that "Mbu's football character and size give him a shot to make an NFL team.

[22] After the AAF suspended football operations, Mbu signed with the Miami Dolphins on April 9, 2019 alongside fellow San Antonion teammate Elliott.

[24] In October 2019, Mbu was selected by the New York Guardians in the second round of the 2020 XFL Draft.