John Adams College and Career Academy is a public high school located on the east side of Cleveland, Ohio, United States.

John Adams High School opened at East 116th Street and Corlett Avenue in 1923.

It was closed in 1995, along with West Technical, and Aviation High Schools to help cut the city's budget.

In 2014 it adopted a new rule requiring polo shirts with monogrammed school logos.

The primary rivals for the school's sports teams are the John F. Kennedy Eagles, who are located nearby, and the James Ford Rhodes Rams on the west side.