John Calvin Lee (January 7, 1828 – March 24, 1891) was an American Republican politician and soldier who served as the ninth lieutenant governor of Ohio from 1868 to 1872.

He served for a short time as president of a court-martial convened by order of General Rosecrans at Charleston, and then joined his regiment at Romney.

He was in the battles of Freeman's Ford, White Sulphur Springs, Warrenton, Bristow's Station, New Baltimore, New Market, Thoroughfare Gap, Gainesville, Chantilly, and the Second Bull Run, in all of which he received the special commendation of his superior officers.

At Chancellorsville, in 1863, he was on the right when the enemy made such a furious assault on the eleventh corps, and by his determined efforts, aided by Orland Smith of the Seventy-Third Ohio and McGroarty of the Sixty-First, did much to stay the tide of Rebel success.

When the National Guard was called out he was commissioned Colonel of the One Hundred and Sixty-Fourth Ohio, which did service around the fortifications of Washington.