The John Chambers House is an originally residential building located at 90 North State Street in St. Ignace, Michigan.

"[2][3] The three pooled their money and invested heavily in local real estate, including the first dock built in the city.

[2] Patrick Chambers also entered politics at a local level, serving as Supervisor of Ignace Township and County Treasurer in the 1870s and 80s.

[3] Patrick died in 1916 and Michael in 1918;[6] the house stayed in the family until 1945, when it was sold to a retired ship captain, who used it as an inn from 1947 to 1978.

The older section of the Chambers House is located in the rear; it is a two-story, hipped-roof structure sitting on a rubble foundation.