John Franklin Spalding (August 25, 1828 – March 9, 1902) was a missionary bishop of the Episcopal Church in the United States.

He spent some time as a missionary in Old Town, Maine and in 1859 became rector of St George's Church in Lee, Massachusetts.

In 1860 he became assistant minister at Grace Church in Providence, Rhode Island and a year later also served in St John's Church in Providence, Rhode Island.

Between 1862 and 1873 he served as rector of St Paul's Church in Erie, Pennsylvania.

Spalding wrote a number of books including A Devotional Manual, Jesus Christ, Proof of Christianity, several tracts and numerous occasional sermons and addresses.