As bishop's chancellor in Ely, Cambridgeshire, he was charged with suppressing Christian heresy, condemning several heretics to be burnt at the stake.
[1] In 1547 he served as rector of Hanwell, Middlesex, but resigned the charge in 1551, having in 1550 been appointed vicar-general or chancellor to Thomas Thirlby, bishop of Norwich.
For example, during the period that became known as the Marian Persecutions, two men from Wisbech, constable William Wolsey and painter Robert Pygot, were condemned by Fuller at Ely on 9 October 1555.
[3] He was proctor for the clergy of the diocese in two convocations, and held other preferments, being rector of Wilbraham, Fen Ditton, and Hildersham, Cambridgeshire.
[5] Fuller was buried, according to his directions, in the choir of Jesus College, to which institution he bequeathed one-third of his property, besides founding four fellowships.