The John G. Ayling House is a historic house located at 223 DeWitt Street in the Sedgwick neighborhood of Syracuse, Onondaga County, New York.

It is a two-story, Tudor Revival style asymmetrical dwelling.

It is sheathed in stucco and half-timbering and has a steep cross-gabled roof.

The house features diamond paned and leaded glass windows and American Craftsman inspired Moravian tiles.

[1] In 2015, the house was bought by writers Jonathan Dee and Dana Spiotta, who began residing there.