His mother was the Honourable Caroline Jane,[1] daughter of James Stuart-Wortley-Mackenzie, 1st Baron Wharncliffe, grandson of Prime Minister John Stuart, 3rd Earl of Bute.
The Right Reverend Edward Talbot, Bishop of Winchester, was his younger brother and Henry Chetwynd-Talbot, 18th Earl of Shrewsbury, his uncle.
Talbot entered Parliament at the 1868 general election for Kent West,[2] a seat he held until 1878, when he resigned to fight a by-election in the Oxford University constituency.
[2] He won the by-election, and held that seat until he stepped down at the January 1910 general election.
[3] He served under Benjamin Disraeli as Parliamentary Secretary to the Board of Trade from 1878 to 1880 and was sworn of the Privy Council in 1897.