In 1895, he was elected to the House of Commons as Member of Parliament (MP) for Derbyshire South, a seat he held until 1906.

He then represented Rutland from the 1907 by-election to 1918 and Burton from 1918 to 1943, when he was appointed an Officer of the Order of St John (OStJ).

[3] Lord Gretton precipitated by a speech the Carlton Club revolt that brought down the Lloyd George Coalition Cabinet in the British Parliament in 1922.

In 1940, Lord Gretton precipitated by a speech the fall of the Neville Chamberlain Government and its replacement by a Coalition.

Maud Helen Eveleigh de Moleyns, youngest daughter of The 4th Baron Ventry, an Anglo-Irish peer.