John James Appleton (September 22, 1792 – March 4, 1864) was an American diplomat who served the United States in several European countries.
John James Appleton studied at Phillips Andover Academy, and graduated from Harvard University in 1813.
In 1825 Appleton was appointed as U.S. special representative to the Kingdom of Naples, where he attempted to settle American claims arising from the seizure and sale of ships and cargo during the government of Joachim Murat.
His daughter Marie married Eugene Pinault, who served as deputy mayor of Rennes, France.
Appleton spent the greater part of his post-diplomatic career in France, making only occasional visits to America.