Jorgenson has recorded or toured with Elton John, Tommy Emmanuel, The Byrds, Bob Dylan, Bob Seger, Willie Nelson, Johnny Cash, Emmylou Harris, Hank Williams Jr., Barbra Streisand, Luciano Pavarotti, Roy Orbison, Patty Loveless, Michael Nesmith, John Prine, and Bonnie Raitt.

In 1993 Jorgenson formed the guitar trio the Hellecasters with Will Ray and guitarist Jerry Donahue of Fairport Convention.

His gypsy jazz ensemble, John Jorgenson Quintet includes Doug Martin (rhythm guitar), Jason Anick (violin), Simon Planting (bass), and Rick Reed (percussion).

The Fender John Jorgenson Signature Custom Korina Telecaster was made at the Fender Custom Shop in 1998, sporting a solid Korina body, a maple neck with pearloid dot inlays and a 25.5" scale length, African rosewood or an ebony on black finish fretboard with 22 Dunlop 6130 frets.

Other features included dual side-by-side Telecaster humbucking pickups, a modified vintage style Tele bridge, a special custom five-way pickup switching featuring five different combinations (each in humbucking mode), 1.688" width at the nut and Sperzel Trimlok locking tuners.

The JJ325SRC and the twelve-string JJ325SRC-12, born from the EF325SRCA, feature a spruce top with bubinga back and sides in a gloss red satin finish, a rosewood fretboard on a mahogany neck with his signature J.J. inlay on the 12th fret, and gold tubes with white pearloid knobs.

Designed in conjunction with Trev Wilkinson, the guitar is packed with a whole host of features including a chambered body, three self-intonating brass saddles, a matched, calibrated set of Wilkinson WVT pickups and two auxiliary ‘ghost’ coils which provide both hum-cancelling and classic single coil tones at the turn of a dial, thanks to the unique ‘Vari-coil’ control.

With The Desert Rose Band With The Hellecasters With Kenny Chesney With Rodney Crowell With Jerry Donahue With Firefall With Neal McCoy With Michael Nesmith With Syd Straw With others