He was a partner in the firm Kuhn, Loeb & Co., as well as a trustee of the John Simon Guggenheim Memorial Foundation, a breeder of championship thoroughbred racehorses, and the national president of the Boy Scouts of America from 1951 to 1956.
Both John Schiff and his father were notable early Boy Scouts of America leaders.
He was the breeder of the 1970 American Champion Two-Year-Old Colt Hoist the Flag and successfully raced a number of horses including Plugged Nickle and Droll Role.
John Schiff married Edith Brevoort Baker, granddaughter of George Fisher Baker who was called "the richest, most powerful and most taciturn commercial banker in U. S. history" in a 1934 TIME magazine article.
His son David served as chairman of Wildlife Conservation Society[7] and married Martha Elizabeth Lawler in an Episcopal ceremony in 1963.