Lieutenant-Colonel John Manners-Sutton (29 July 1752 – 17 February 1826) was a British soldier and politician who sat in the House of Commons from 1783 to 1796.
Manners-Sutton was elected Member of Parliament for Newark at a by-election in 1783.
He succeeded his brother George Manners-Sutton, inheriting Kelham Hall near Newark, Nottinghamshire, and was appointed High Sheriff of Nottinghamshire for 1808–09.
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