John Munford Gregory (July 8, 1804 – April 9, 1884) was a US political figure and Acting Governor of Virginia from 1842 to 1843.

He served as acting Governor of Virginia from 1842 to 1843 and then as a state court judge in Virginia Gregory died on April 9, 1884, and was buried at Shockoe Hill Cemetery in Richmond, Virginia.

One of the enslaved people that Gregory hired, John Dunjee, escaped and became a prominent Baptist preacher.

His home at Richmond after 1849, the Benjamin Watkins Leigh House, was listed on the National Register of Historic Places in 1969.

This article about a member of the Virginia House of Delegates is a stub.