Before 1512 he was appointed attorney to the earldom of Chester, and in that year he appeared as one of the commissioners selected to inquire into the extortions of the masters of the mint.

In 1535 he was placed on the commission of oyer and terminer for Middlesex to try John Fisher and Thomas More, and in the following year was similarly employed with regard to Anne Boleyn.

He gave to it a garden lying on the south side of the college, and completed John Williamson's bequest of £200 to provide stipends for two sufficient and able persons to read and teach openly in the hall, the one philosophy, the other 'humanity.

The stipend was (then) 4 shillings a year, but the limitation to the descendants of Williamson and Port was abolished by Oxford University in 1854.

[5] Port married firstly Joan FitzHerbert, widow of John Pole of Radbourne, Derbyshire, and the daughter and coheir of John FitzHerbert (d.1502), King's Remembrancer of the Exchequer, by whom he had a son, Sir John Port, and three daughters:[3][6] Port married secondly, in the 1520s, Margery Trafford (d.1540), widow of Sir Thomas Gerard (d. 1523), and daughter of Sir Edmund Trafford of Trafford, Lancashire, by whom he had no issue.