From 1992 to 1998, he was a member of the country band Lonestar, in which he played bass guitar and alternated with Richie McDonald as lead vocalist.

In 2001, he self-released Rescue Me, an album he was inspired to record by a cancer patient named Katie Darnell.

These albums accounted for ten singles on the country charts, including the Number One "Lost in This Moment".

A fourth Big & Rich studio album was released in the summer of 2012, with the inspiring "That's Why I Pray" reaching No.

In the same time span, he co-wrote multiple singles for other artists, including the Number One hits "Redneck Woman" for Wilson, "Mississippi Girl" for Faith Hill and "Why" for Jason Aldean.

In 2016, Rich added his voice to a duet with Marie Osmond on her album Music Is Medicine with the song titled "Love This Tough".

The song, "Another You", is the lead-off single to Rich's second studio album, Son of a Preacher Man, which was released on March 24, 2009.

Rich promoted the song, which addresses the Chrysler and General Motors bailouts, at Michigan radio stations.

Rich also served as a judge on the 2008 version of Nashville Star on NBC along with Jewel, singer-songwriter Jeffrey Steele, and host Billy Ray Cyrus.

Despite the first loss, he later won 2 more tasks as Project Manager, raising $1,266,908 for St. Jude Children's Research Hospital.

He endorsed the Conservative Party candidate Doug Hoffman in the special congressional election in Northern New York in 2009.

[11] On April 7, 2015, Rich's song "Shuttin' Detroit Down" was featured in Senator Rand Paul's 2016 presidential campaign announcement.

[13] Big & Rich would later perform at a pre-inaugural ceremony on January 19, 2017, after Trump's victory in the general election.

In April 2023, Rich was one of many musicians to express support for the Bud Light boycott, announcing that he would no longer sell Anheuser-Busch products at his bar.