John Sanford Cohen (February 26, 1870 – May 13, 1935) was a United States senator from Georgia.

His maternal grandfather was politician and Confederate Civil War general Ambrose R.

He attended the United States Naval Academy in 1885 and 1886, and became a newspaper reporter for the New York World in 1886.

Cohen was appointed on April 25, 1932 to the United States Senate as a Democrat to fill the vacancy caused by the death of William J. Harris and served from April 25, 1932 to January 11, 1933, when a successor was duly elected and qualified.

He was not a candidate in 1932 to fill the vacancy, and continued his former business activities until his death in Atlanta.