[8][9][1] In 1976, the two co-founded SAS Institute, an analytics software company, with fellow NCSU alumni Anthony James Barr and Jane Helwig.

[5] Some of his contributions included procedures for working with time series, econometrics, categorical data and matrix algebraic manipulations.

[12] SAS Institute grew rapidly,[13] becoming one of the largest privately held software providers in the world[14] and earning $3.2 billion in annual revenue as of 2022.

[16] During this time, the company has invested heavily into the research and development of artificial intelligence tools designed for industries like finance, healthcare, and insurance.

[18] Sall and a small team of developers spent a year and a half working on JMP before version one was released in October 1989.

[8]  According to Forbes, Sall's net worth was approximately $4.2 billion as of 2016, making him the 392nd richest person in the United States at the time.

[24] Sall and his wife also work with the World Wide Fund for Nature (WWF), CARE, Pan American Health Organization, and other non-profits.