John Senio (born 10 September 1982) is a Samoan rugby union footballer.

He last played for French club FC Grenoble in the Pro D2.

Prior to signing with Grenoble he played for Bourgoin ASM Clermont Auvergne, Edinburgh Rugby in the Celtic League and the New Zealand franchise the Blues in the Super 14.

He has also played for the Samoan national team, and was a member of their 2003 Rugby World Cup squad.

This biographical article relating to Samoan rugby union is a stub.