Woodhouse remarried on April 26, 1913, in Detroit, Michigan to his second wife, Elizabeth E. Ewing, daughter of John Timothy Ewing and Elizabeth Johnson, but the couple divorced on December 17, 1926, in Detroit, Michigan.

In the meantime, John T. Woodhouse & Company continued to grow, and moved into a new headquarters in downtown Detroit where Hart Plaza is now located.

Woodhouse moved into this house once it was built, and in the late 1920s turned his business over to his son, John Thompson Woodhouse Jr. Woodhouse remarried to his third wife Clara S. Frederick, daughter of Charles N. Frederick and Selma Dreher, on August 19, 1929, in Niagara Falls, New York, but financial losses due to the Great Depression caused him despair, and he committed suicide in this house on January 25, 1930.

The Woodhouse house has a combination gable and hip roof, and is finished in rock-face random ashlar limestone on the first story and stucco above.

The original front, once visible from Lake Shore Road, has a center entrance with an elaborate stone pediment above containing garlands of fruit and the sculptured head of the Greek goddess Hera.

On the other side of the house, the current main entrance is in the center of an irregular facade.

[3] The original address of the John Thompson Woodhouse home was 337 lake Shore Drive, Grosse Pointe Farms, Wayne County, Michigan, USA.

The John Thompson Woodhouse palatial home was modeled after Scale Hall in Skerton, Ecclesiastical District of St. Luke's, Lancashire, England, which had been occupied by one branch of the Woodhouse family for generations.