John Twiggs Myers (January 29, 1871 – April 17, 1952) was a United States Marine Corps general who was most famous for his service as the American Legation Guard in Beijing during the Boxer Rebellion.

In May 1900, Myers was sent to China aboard the cruiser USS Newark and put ashore with a detachment of 48 Marines (including then Private Daniel Daly) and 3 sailors to guard the US Legation in Beijing, just as the Boxer Rebellion broke out.

Myers was wounded in the leg by a spear; his attack was claimed by the British Consul, Sir Claude Maxwell MacDonald, as "one of the most successful operations of the siege, as it rendered our position on the wall, which had been precarious, comparatively strong."

In the historical epic 55 Days at Peking, Charlton Heston portrayed Marine Major Matt Lewis, commanding the American Legation Guard in Beijing during the Boxer Rebellion.

In The Wind and the Lion, the fictional Captain Jerome (played by Steve Kanaly) took on Myers' historical role, commanding the Marines dispatched to Tangier during the Perdicaris affair.