The John Wilson House is a historic dwelling located southwest of De Soto, Iowa, United States.

John Wilson was a part of a migration of Quakers from Indiana into Iowa beginning in the 1830s.

[2] Wilson and his family initially settled in Warren County in 1853.

Wilson built this two-story house of locally quarried limestone in 1861.

This article about a property in dallas County, Iowa on the National Register of Historic Places is a stub.