John Wood Lewis Sr. (February 1, 1801 – July 11, 1865) was an American politician and physician who represented Georgia in the Confederate States Senate from 1862 to 1863.
He attended Cedar Springs Academy, and then studied medicine under Richard Harris of Greenville.He subsequently established a medical practice in Spartanburg.
[3] Lewis began buying land, building iron furnaces, and improving roads leading to or crossing his property.
Having established himself as a successful businessman, Lewis was elected as a Democrat to the Georgia State Senate in 1845 and served one term.
Brown wrote to Lewis saying "I did not deserve this at your hands, and I confess I felt it keenly...I do not attribute improper motives, but only say the coincidence was an unfortunate one for me".