[1] Guise served with his regiment in the Ferrol Expedition, Vigo, and Cadiz in 1800, in Egypt in 1801, in Hanover in 1805–06, and accompanied it to Portugal in 1809.
At the investment of and repulse of the sortie from Bayonne, he succeeded to the command of the second brigade of Guards when Maj-Gen Edward Stopford was wounded (gold cross and war medal).
[1] Guise became a major-general in 1819, was appointed CB in 1831, became a lieutenant-general and KCB in 1841, colonel 85th light infantry in 1847, general 1851, and was made GCB 1863.
[1] In 1863 he was granted heraldic supporters (usually only borne by peers) to descend to heirs male of the body on succession to the baronetcy.
They had seven children: Of the several estates he inherited from his brother in 1834, he sold Rendcombe, Eighnam and Brockworth, retaining Highnam, Elmore and Rodley.